I don’t really struggle with hay fever but it hit me hard on a trip to Japan
*Histamines. Antibodies are far less disruptive. Histamines protect us from larger invaders like worms and other parasites. Antihistamines antagonize histamines at receptor sites, preventing the itchy, red, swelling reaction we associate with an allergen.
Acktually – IgE(/antibodies) are bound to the surface of mast cells. Antigens/allergens bind to the IgE receptor and actives the mast cell, releasing histamines. Allergy can actually be treated with anti-IgE (monoclonal) antibodies (Omalizumab)!
Thank you for the detail! I just repeated the dumbed-down explanation given to me by my allergist.
“Welcome. You will experience a tingling sensation and then death.”
FREAK OUT ACTIVATED
is more like it
